SB-216641 (hydrochloride), CAS 193611-67-5

Formulation: A solid

Formal Name: N-[3-[2-(dimethylamino)ethoxy]-4-methoxyphenyl]-2′-methyl-4′-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1′-biphenyl]-4-carboxamide, monohydrochloride

Purity: ≥98%

Formula Markup: C28H30N4O4 • HCl

Formula Weight: 523

Shelf life (days): 1460

CAS Number: 193611-67-5

Notes: SB-216641 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT1B.{54405} It binds to 5-HT1B receptors (Ki = 1 nM) and is selective for 5-HT1B over 5-HT1A, 5-HT1D, 5-HT1E, and 5-HT1F receptors in radioligand binding assays (Kis = 500, 25, >1,000, and >1,000 nM, respectively). SB-216641 (1-1,000 nM) reduces 5-HT-induced inhibition of forskolin-induced cAMP production in CHO cells expressing human 5-HT1B receptors.

• SKU: CAY32837-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 32837-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK