SB-611812, CAS 345892-71-9

Formulation: A solid

Formal Name: 2,6-dichloro-N-[4-chloro-3-[2-(dimethylamino)ethoxy]phenyl]-4-(trifluoromethyl)-benzenesulfonamide

Purity: ≥98%

Formula Markup: C17H16Cl3F3N2O3S

Formula Weight: 491,7

Shelf life (days): 1460

CAS Number: 345892-71-9

Notes: SB-611812 is an antagonist of the urotensin II receptor (UTR).{57405} It binds to recombinant rat UTR (Ki = 121 nM) and inhibits contraction of isolated rat aorta induced by urotensin II (pA2 = 6.59) but not potassium chloride, endothelin-1, angiotensin II, or phenylephrine. SB-611812 (30 mg/kg) decreases myocardial interstitial fibrosis and the ratio of collagen I to collagen III in a rat model of ischemia induced by ligation of the left anterior descending (LAD) artery.{57406}

• SKU: CAY33247-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 33247-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK