SB-674042, CAS 483313-22-0

Formulation: A crystalline solid

Formal Name: [5-(2-fluorophenyl)-2-methyl-4-thiazolyl][(2S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-1-pyrrolidinyl]-methanone

Purity: ≥98%

Formula Markup: C24H21FN4O2S

Formula Weight: 448,5

Shelf life (days): 1460

CAS Number: 483313-22-0

Notes: SB-674042 is a potent and selective non-peptide orexin 1 receptor (OX1R) antagonist (Kd = 5.03 and 3.76 nM in whole cell binding and membrane-based assays, respectively).{34091} In calcium mobilization studies, it was >100-fold selective for OX1 over OX2 and did not show significant affinity for serotonergic, dopaminergic, adrenergic, or purinergic receptors at concentrations up to 10 µM.{34090}

• SKU: CAY21270-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21270-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK