SB-756050, CAS 447410-57-3

Formulation: A crystalline solid

Formal Name: 1,4-bis[(3,4-dimethoxyphenyl)sulfonyl]hexahydro-1H-1,4-diazepine

Purity: ≥95%

Formula Markup: C21H28N2O8S2

Formula Weight: 500,6

Shelf life (days): 1460

CAS Number: 447410-57-3

Notes: SB-756050 is an agonist of the bile acid G protein-coupled receptor TGR5 (EC50 = 1.3 μM for the human receptor).{45338} It is selective for TGR5 over the farnesoid X receptor (FXR) and a panel of other receptors, channels, and transporters. SB-756050 (10-100 mg/kg) decreases fasting glucose levels and increases glucose disposal rate and insulin secretion in diabetic Goto Kakizaki rats.

• SKU: CAY27998-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 27998-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK