Scopine (hydrochloride), CAS 85700-55-6

Formulation: A crystalline solid

Formal Name: (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, monohydrochloride

Purity: ≥95%

Formula Markup: C8H13NO2 • HCl

Formula Weight: 191,7

Shelf life (days): 1460

CAS Number: 85700-55-6

Notes: Scopine is a metabolite of the muscarinic antagonist scopolamine.{43932} Scopine binds to muscarinic acetylcholine receptors with an IC50 value of 3 µM and is selective for muscarinic acetylcholine receptors over nicotinic acetylcholine receptors (IC50 = >500 µM).{43933} It reduces hyperphagia induced by the antipsychotics loxapine (Item No. 20760) and chlorpromazine (Item No. 16129) in C. elegans without affecting basal feeding.{43934} When conjugated to chlorambucil, scopine improves the blood-brain barrier permeability of chlorambucil (Item No. 23744).{43935}

• SKU: CAY27052-250
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 27052-250
• Green Labware: No
• Package Unit: 250 mg
• Quantity Unit: STK