Secretin (rat) (trifluoroacetate salt)

Formulation: A lyophilized powder

Purity: ≥95%

Formula Markup: C129H216N42O42 • XCF3COOH

Formula Weight: 3027,4

Shelf life (days): 1460

Notes: Secretin is a neuropeptide hormone that regulates secretion from the stomach, pancreas, and liver.{38733,38734} It binds to the rat secretin receptor (SCT-R; Ki = 3.3 nM) and increases intracellular cAMP (EC50 = 1 nM) in COS cells expressing rat SCT-R.{38735} It also increases SCT-R phosphorylation 7.2-fold at a concentration of 0.1 μM. Secretin dose-dependently increases the volume of pancreatic secretion and inhibits gastric acid secretion induced by gastrin I (Item No. 24457) in rats when administered at a dose of 100 pmol/kg per hour.{38736}

• SKU: CAY24561
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 24561-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK