STING Agonist 12b, CAS 2411100-70-2

Formulation: A crystalline solid

Formal Name: 2-methoxy-5,6-dimethyl-9(10H)-acridinone

Purity: ≥98%

Formula Markup: C16H15NO2

Formula Weight: 253,3

Shelf life (days): 730

CAS Number: 2411100-70-2

Notes: STING agonist 12b is an agonist of stimulator of interferon genes (STING).{59528} It binds to STING (Kd = 26.4 µM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 µM, respectively). STING agonist 12b (40 µM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.

• SKU: CAY32521-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 32521-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK