Formulation: A solid
Formal Name: 6-β-D-glucopyranosyl-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one
Purity: ≥98%
Formula Markup: C22H22O10
Formula Weight: 446,4
Shelf life (days): 1460
CAS Number: 6991-10-2
Notes: Swertisin is a flavonoid C-glycoside that has been found in Swertia japonica and has diverse biological activities.{61674,61675,61676} It inhibits sodium-glucose cotransporter 2 (SGLT2) in HEK293 cells when used at a concentration of 7.5 µg/ml and is an adenosine A1 receptor antagonist (IC50 = 137 µM).{61674,61675} Swertisin (0.2-5 µM) inhibits hepatitis B virus (HBV) replication in HepG2 2.2.15 cells.{61676} It decreases blood glucose levels in a mouse model of diabetes induced by streptozotocin (Item No. 13104), as well as prevents scopolamine-induced increases in escape latency in the Morris water maze in mice.{61674,61675}
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