Tazarotenic Acid, CAS 118292-41-4

Tazarotenic Acid, CAS 118292-41-4
SKU
CAY21367-50
Packaging Unit
50 mg
Manufacturer
Cayman Chemical

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Formulation: A crystalline solid

Formal Name: 6-[2-(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]-3-pyridinecarboxylic acid

Purity: ≥98%

Formula Markup: C19H17NO2S

Formula Weight: 323,4

Shelf life (days): 1460

CAS Number: 118292-41-4

Notes: Tazarotenic acid is a retinoic acid receptor (RAR) agonist and an active metabolite of the retinoid prodrug tazarotene (Item No. 23559).{51249} It induces reporter gene expression in DK7-NR cells expressing human RARα, RARβ, or RARγ (EC50s = 11, 2.5, and 11 nM, respectively). Topical application of tazarotenic acid (0.1% w/w) reduces ear edema in a mouse model of epidermal inflammation induced by phorbol 12-myristate 13-acetate (PMA; Item No. 10008014).
More Information
SKU CAY21367-50
Manufacturer Cayman Chemical
Manufacturer SKU 21367-50
Green Labware No
Package Unit 50 mg
Quantity Unit STK
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