Formulation: A crystalline solid
Formal Name: 5,8,13,13a-tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine
Purity: ≥98%
Formula Markup: C20H21NO4
Formula Weight: 339,4
Shelf life (days): 1460
CAS Number: 522-97-4
Notes: Tetrahydroberberine is an isoquinoline alkaloid that has been found in C. turtschaninovii and has diverse biological activities.{59807,59808,59809,59810} It inhibits iron- and ascorbate-induced lipid peroxidation in rat liver microsomes (IC50 = 13.7 µM).{59807} Tetrahydroberberine binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtype 5-HT1A (Kis = 0.83 and 4.2 µM, respectively).{59808} It inhibits potassium currents induced by acetylcholine (Item No. 23829) in primary rat hippocampal CA1 pyramidal neurons (IC50 = 13 µM).{59809} Tetrahydroberberine stimulates mouse C12C12 myoblast differentiation in a concentration-dependent manner.{59810}
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