Formulation: A solid
Formal Name: 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-di(methyl-d3)-ethanamine
Purity: ≥99% deuterated forms (d1-d6)
Formula Markup: C26H22ClD6NO
Formula Weight: 412
Shelf life (days): 1460
Notes: Toremifene-d6 is intended for use as an internal standard for the quantification of toremifene (Item No. 20854) by GC- or LC-MS. Toremifene is an orally bioavailable selective estrogen receptor modulator (SERM) that evokes tissue-dependent effects similar to that of tamoxifen (Item No. 13258 / 11629).{23588} It has been shown to block estrogen-stimulated growth of MCF-7 breast cancer cells grown in tissue culture, to inhibit ovariectomy-induced bone loss in rats, and to stimulate endometrial growth similar to that of tamoxifen.{23588}