Tozadenant, CAS 870070-55-6

Tozadenant, CAS 870070-55-6
SKU
CAY28452-50
Packaging Unit
50 mg
Manufacturer
Cayman Chemical

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Formulation: A crystalline solid

Formal Name: 4-hydroxy-N-[4-methoxy-7-(4-morpholinyl)-2-benzothiazolyl]-4-methyl-1-piperidinecarboxamide

Purity: ≥98%

Formula Markup: C19H26N4O4S

Formula Weight: 406,5

Shelf life (days): 1460

CAS Number: 870070-55-6

Notes: Tozadenant is an adenosine A2A receptor antagonist (Kis = 11.5 and 6 nM for the human and rhesus monkey receptors, respectively).{47787} It increases the distance traveled and reduces contralateral asymmetry in the open field test in a rat model of Parkinson's disease induced by 6-OHDA (Item No. 25330) when administered at a dose of 30 mg/kg.{47788} Tozadenant (150 mg/kg) reverses locomotor deficits and restores novel object-stimulated locomotion in a marmoset model of MPTP-induced Parkinson's disease.{47789}
More Information
SKU CAY28452-50
Manufacturer Cayman Chemical
Manufacturer SKU 28452-50
Green Labware No
Package Unit 50 mg
Quantity Unit STK
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