trans-10-hydroxy Nortriptyline, CAS 47132-16-1

Formulation: A solid

Formal Name: (5E)-10,11-dihydro-5-[3-(methylamino)propylidene]-5H-dibenzo[a,d]cyclohepten-10-ol

Purity: ≥90%

Formula Markup: C19H21NO

Formula Weight: 279,4

Shelf life (days): 1460

CAS Number: 47132-16-1

Notes: trans-10-hydroxy Nortriptyline is an active metabolite of the tricyclic antidepressants amitriptyline (Item No. 15881) and nortriptyline (Item No. 15904).{61943,61944} It is formed from amitriptyline and nortriptyline by the cytochrome P450 (CYP) isoform CYP2D6.{61943} trans-10-hydroxy Nortriptyline inhibits norepinephrine reuptake in rat cortical slices and isolated human plasma (EC50s = 160 and 176 nM, respectively).{61944}

• SKU: CAY36660-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36660-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe