TRAP-6 amide (trifluoroacetate salt)

Formulation: A solid

Formal Name: (S)-2-((2S,5S,8S,11S,14S)-14-amino-11-benzyl-2-(3-guanidinopropyl)-15-hydroxy-5,8-diisobutyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecanamido)succinamide

Purity: ≥95%

Formula Markup: C34H57N11O8 • XCF3COOH

Formula Weight: 747,9

Shelf life (days): 1460

Notes: TRAP-6 amide is a peptide agonist of proteinase-activated receptor 1 (PAR1).{69061} It induces platelet aggregation in vitro (EC50 = 0.15 µM). TRAP-6 amide (30 µM) induces relaxation of isolated guinea pig internal anal sphincter strips.{69062} It also increases cigarette smoke extract-induced IL-8 release from isolated human bronchial epithelial cells when used at a concentration of 50 µM.{69063}

• SKU: CAY36881-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36881-5
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe