Triptophenolide, CAS 74285-86-2

Formulation: A solid

Formal Name: (3bR,9bS)-3b,4,5,9b,10,11-hexahydro-6-hydroxy-9b-methyl-7-(1-methylethyl)-phenanthro[1,2-c]furan-1(3H)-one

Purity: ≥98%

Formula Markup: C20H24O3

Formula Weight: 312,4

Shelf life (days): 1460

CAS Number: 74285-86-2

Notes: Triptophenolide is a diterpenoid that has been found in T. wilfordii and has antiandrogenic activity.{63171} It is an antagonist of wild-type and mutant androgen receptors (ARs; IC50s = 260, 388, 480, and 437 nM for wild-type, ART877A, ARF876L, and ARW741C/T877A, respectively, in transactivation assays). Triptophenolide (5 µM) inhibits the growth of, and reduces AR levels in, LNCaP prostate cancer cells.

• SKU: CAY34390-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34390-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK