UNC6934, CAS 2561494-77-5

Formulation: A solid

Formal Name: N-cyclopropyl-3,4-dihydro-3-oxo-N-[[4-[(4-pyrimidinylamino)carbonyl]phenyl]methyl]-2H-1,4-benzoxazine-7-carboxamide

Purity: ≥98%

Formula Markup: C24H21N5O4

Formula Weight: 443,5

Shelf life (days): 1460

CAS Number: 2561494-77-5

Notes: UNC6934 is an inhibitor of the protein-protein interaction between histone-lysine N-methyltransferase NSD2 and dimethylated lysine 36 histone 3 (H3K36me2) nucleosomes (IC50 = 104 nM).{72186} It binds to NSD2 (Kd = 92 nM). UNC6934 also inhibits the serotonin transporter (SERT) and μ-opioid receptor (Kis = 1.4 and 8 µM, respectively). It induces NSD2 nucleolus accumulation in U2OS cells when used at a concentration of 5 µM.

• SKU: CAY28814-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28814-5
• Package Unit: 5 mg
• Quantity Unit: STK