Formulation: A solid
Formal Name: 5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)benzofuran-2-carboxamide
Purity: ≥99% deuterated forms (d1-d8)
Formula Markup: C26H19D8N5O2
Formula Weight: 449,6
Shelf life (days): 1460
CAS Number: 1794789-93-7
Notes: Vilazodone-d8 is intended for use as an internal standard for the quantification of vilazodone (Item No. 21547) by GC- or LC-MS. Vilazodone is a selective serotonin reuptake inhibitor (SSRI) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A (IC50s = 0.2 and 0.5 nM, respectively).{33581} It increases extracellular 5-HT in the rat ventral hippocampus and frontal cortex when administered intraperitoneally at doses of 1 and 3 mg/kg, respectively. Vilazodone (1 mg/kg, i.p.) decreases immobility in the forced swim test in both rats and mice. Formulations containing vilazodone have been used in the treatment of depression.
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