Formulation: A crystalline solid
Formal Name: αR-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
Purity: ≥95%
Formula Markup: C22H28FNO3
Formula Weight: 373,5
Shelf life (days): 1460
CAS Number: 139290-65-6
Notes: Volinanserin is a potent and selective antagonist of the serotonin receptor 5-HT2A (Ki = 0.36-0.85 nM).{25877,25875} It weakly binds 5-HT2C, α1-adrenergic, and sigma receptors (Ki = 88, 128, and 87 nM) and much less effectively associates with other serotonin, dopamine, adrenergic, muscarinic acetylcholine receptors and monoamine transporters.{25875,25876} Volinanserin displays antipsychotic activity, attenuates impulsivity, and augments antidepressant effects in vivo.{25877,25878,23022}