WaTx (36-68) (scorpion) (trifluoroacetate salt)

Formulation: A solid

Formal Name: L-alanyl-L-seryl-L-prolyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-tyrosyl-L-α-glutamyl-L-glutaminyl-L-cysteinyl-L-asparaginyl-L-valyl-L-asparaginyl-L-lysyl-L-valyl-L-prolyl-L-phenylalanyl-L-α-aspartyl-L-glutaminyl-L-cysteinyl-L-tyrosyl-L-glutaminyl-L-methionyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-α-glutamyl-L-arginyl-L-serine, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C164H245N45O53S5 • XCF3COOH

Notes: Wasabi receptor toxin (WaTx) (36-68) is a cell-penetrating peptide that corresponds to the mature toxin sequence and is an activator of transient receptor potential ankyrin 1 (TRPA1).{72198} It selectively induces currents in HEK293T cells expressing human TRPA1 (EC50 = 15 nM) over cells expressing human TRP melastatin 8 (TRPM8) or human TRP vanilloid 1 (TRPV1) at 100 nM or rat voltage-gated potassium channel 1.2 (Kv1.2), rat Kv2.1, rat Kv3.1, or rat Kv4.3 at 1,000 nM. WaTx induces nocifensive behavior in wild-type but not Trpa1-/- mice.

• SKU: CAY37495-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37495-5
• Package Unit: 5 mg
• Quantity Unit: STK