Yamogenin, CAS 512-06-1

Formulation: A solid

Formal Name: (3β,25S)-spirost-5-en-3-ol

Purity: ≥98%

Formula Markup: C27H42O3

Formula Weight: 414,6

Shelf life (days): 1460

CAS Number: 512-06-1

Notes: Yamogenin is a steroidal sapogenin that has been found in fenugreek (T. foenum graecum) and has diverse biological activities.{64666,64667} It inhibits activation of the liver X receptor (LXR) induced by the LXRα and LXRβ agonist T0901317 (Item No. 71810) in HepG2 cells in a reporter assay when used at concentrations of 5 or 10 µM.{64666} Yamogenin (10 µM) decreases triglyceride levels in primary mouse hepatocytes. It is cytotoxic to HaCaT keratinocytes, as well as HeLa cervical and SKOV3 ovarian cancer cells (IC50s = 16.4, 19.6, and 23.9 µg/ml, respectively).{64667}

• SKU: CAY36008-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36008-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe