YCT529

Formulation: A solid

Formal Name: 4-(5-(2,2-dimethyl-4-(p-tolyl)-2H-chromen-6-yl)-1H-pyrrol-2-yl)benzoate, sodium salt

Purity: ≥98%

Formula Markup: C29H24NO3 • XNa

Formula Weight: 434,5

Shelf life (days): 1460

Notes: YCT529 is an antagonist of retinoic acid receptor α (RARα; IC50 = 6.8 nM).{68693} It is selective for RARα over RARβ and RARγ (IC50s = >3,700 nM for both). YCT529 (7.5 mg/kg per week) reversibly reduces epidydimal sperm counts without reducing serum testosterone levels in male mice. It reduces germinal epithelial thickness in male dogs when administered at a dose of 25 mg/kg per day. YCT529 (10 mg/kg per week) decreases the number of embryos formed following copulation when administered to male rats.

• SKU: CAY39995-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 39995-1
• Package Unit: 1 mg
• Quantity Unit: STK