Zamifenacin (fumarate), CAS 127308-98-9

Formulation: A solid

Formal Name: (3R)-1-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(diphenylmethoxy)-piperidine, (2E)-2-butenedioate

Purity: ≥98%

Formula Markup: C27H29NO3 • C4H4O4

Formula Weight: 531,6

Shelf life (days): 1460

CAS Number: 127308-98-9

Notes: Zamifenacin is an antagonist of M3 muscarinic acetylcholine receptors (Ki = 10 nM for the human receptor).{59723} It is selective for M3 over M1, M2, M4, and M5 receptors in radioligand binding assays using cells expressing recombinant human receptors (Kis = 55, 153, 68, and 34 nM, respectively). Zamifenacin inhibits cholecystokinin-induced small bowel motility (ED50 = 0.9 mg/kg) but does not increase heart rate (ED150 = 80.0 mg/kg) in dogs.{59725}

• SKU: CAY32848-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 32848-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK