ZB716, CAS 1853279-29-4

Formulation: A solid

Formal Name: B-[(7α,17β)-17-hydroxy-7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-trien-3-yl]-boronic acid

Purity: ≥95%

Formula Markup: C32H48BF5O4S

Formula Weight: 634,6

Shelf life (days): 1460

CAS Number: 1853279-29-4

Notes: ZB716 is a degrader of estrogen receptor α (ERα; IC50 = 4.1 nM).{66937} It inhibits estradiol-induced ERα transcriptional activity in a reporter assay using T47D cells when used at concentrations of 1 or 10 nM. ZB716 decreases the proliferation of MCF-7 and T47D breast cancer cells and tamoxifen-resistant MCF-7 and T47D cells (IC50s = 0.0032, 0.0062, 0.069, and 0.037 nM, respectively).

• SKU: CAY42238-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42238-500
• Package Unit: 500 µg
• Quantity Unit: STK