Zymosan A, CAS 58856-93-2

Formulation: A powder

Shelf life (days): 1460

CAS Number: 58856-93-2

Notes: Zymosan A is a glucan derived from the cell wall of S. cerevisiae that activates toll-like receptor 2 (TLR2) and a C-type lectin, dectin-1, on macrophages, monocytes, and dendritic cells to induce inflammatory signaling.{33697,33696,33699,33701} It is commonly used to stimulate a sterile inflammatory response in mouse models of sepsis, shock, and peritonitis.{33700,9327} In a mouse model of sepsis/shock, a lethal dose of zymosan A (500 mg/kg) in rats induced inflammation and shock leading to death.{33700} Zymosan A can also induce biosynthesis of eicosanoids.{33698}

• SKU: CAY21175-500
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21175-500
• Green Labware: No
• Package Unit: 500 mg
• Quantity Unit: STK