Formulation: A solid
Formal Name: (S)-6-amino-N-((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S)-35-amino-10,19,22-tris(4-aminobutyl)-4-carbamoyl-7,13,16,25,28-pentaisobutyl-2-methyl-6,9,12,15,18,21,24,27,30-nonaoxo-5,8,11,14,17,20,23,26,29-nonaazapentatriacontan-31-yl)-2-((S)-2-((S)-2-((S)-6-amino-2-((S)-2-amino-4-methylpentanamido)hexanamido)-4-methylpentanamido)-4-methylpentanamido)hexanamide, trifluoroacetate salt
Purity: ≥98%
Formula Markup: C90H174N22O15 • XCF3COOH
Formula Weight: 1804,5
Shelf life (days): 1460
Notes: L-K6L9 is a cytolytic peptide composed of L-isomers of leucine and lysine.{65792} It is cytotoxic to LNCaP-CL1 androgen-independent, as well as 22Rv1 and LNCaP androgen-dependent, human prostate cancer cells (LC50s = 4, 4, and 6 µM, respectively), as well as non-cancerous NIH3T3 mouse fibroblasts and OL human foreskin fibroblasts (LC50s = 7 and 5 µM, respectively). It induces hemolysis of isolated human erythrocytes when used at a concentration of 100 µM.
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