Formulation: A solid
Formal Name: 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid, 9-octanoate
Purity: ≥98%
Formula Markup: C21H36N4O8
Formula Weight: 472,5
Shelf life (days): 730
CAS Number: 203120-46-1
Notes: Laninamivir octanoate is an inhibitor of influenza neuraminidases and a prodrug form of laninamivir.{49847} It selectively inhibits the neuraminidases from influenza A H1N1, H2N2, and H3N2 strains (mean IC50s = 822, 128, and 114 nM, respectively) over the neuraminidases from influenza B Victoria and Yamagata strains (mean IC50s = >10,000 nM for both). Intranasal administration of laninamivir octanoate (0.95 µg/kg) increases survival in a mouse model of lethal influenza H1N1 infection. Formulations containing laninamivir octanoate have been used in the prevention of influenza.
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