LGALS8 Recombinant Protein

Conjugation: Unconjugated

Description of Target: Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.

Molecular Weight: 22kDa

Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Protein Name: Galectin-8

Protein Size: Recombinant

Purity: > 95%

Source: E.coli

Tag: N-terminal His Tag

• SKU: AVIOPCD03412-50
• Manufacturer: Aviva Systems Biology
• Manufacturer SKU: OPCD03412-50UG
• Green Labware: No
• Package Unit: 50µg
• Quantity Unit: STK
• Reactivity: Rat (Rattus), Rattus Norvegicus
• Application: Western Blotting, Positive Control, SDS-PAGE
• Host: Escherichia Coli