Recombinant Human ASGR1/ASGPR1 Protein (His Tag)

Protein Construction: Recombinant Human Asialoglycoprotein Receptor 1 is produced by our Mammalian expression system and the target gene encoding Gln62-Ile291 is expressed with a 6His tag at the C-terminus.

Sequence: Gln62-Ile291.

Fusion tag: C-6His.

Accession: P07306.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Mol Mass: 27.4 kDa.

AP Mol Mass: 38 kDa.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Background: Asialoglycoprotein Receptor 1 (ASGPR1) is an endocytic recycling receptor; belongs to the long-form subfamily of the C-type/Ca2+-dependent lectin family. ASGPR consists of two noncovalently-linked subnits; ASGPR1 and ASGPR2. ASGPR1 mediates the endocytosis of plasma glycoproteins; recognizes terminal galactose and N-acetylgalactosamine units. When the ligand binds to to ASGPR1; results in the complex is internalized and transported to a sorting organelle; then ASGPR1 and ligand can be disassociated; ASGPR1 returns to the cell membrane surface.

• SKU: ELSPKSH033403-50
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PKSH033403-50
• Green Labware: No
• Package Unit: 50 µg
• Quantity Unit: STK
• Reactivity: Human
• Host: Human