Recombinant Human Galectin-3/LGALS3 Protein (His Tag)(Active)

Active protein: YES.

Activity: Measured by its ability to agglutinate human red blood cells. .

Protein Construction: Recombinant Human Galectin-3 is produced by our Mammalian expression system and the target gene encoding Ala2-Ile250 is expressed with a 6His tag at the C-terminus.

Sequence: Ala2-Ile250.

Fusion tag: C-6His.

Accession: P17931.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Mol Mass: 27.2 kDa.

AP Mol Mass: 35 kDa.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 3mM DTT.

Background: Galectin-3(LGALS3) is also known as Galactose-specific lectin 3; Mac-2 antigen; Carbohydrate-binding protein 35; Laminin-binding protein and Galactoside-binding protein. LGALS3 is highly expressed in early stages of papillary carcinoma; and lowly during tumor progression. LGALS3 is probably forms homo- or heterodimers and secreted by a non-classical secretory pathway and associates with the cell surface. LGALS3 plays an important role during the acquisition of vasculogenic mimicry and angiogenic properties. LGLAS3 takes part in an immune regulator to inhibit T-cell immune responses and promote tumor growth; as a result providing a new mechanism for tumor immune tolerance.

• SKU: ELSPKSH032473-10
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-PKSH032473-10
• Green Labware: No
• Package Unit: 10 µg
• Quantity Unit: STK
• Reactivity: Human
• Application: Cell Culture
• Host: Human