Formulation: A crystalline solid
Formal Name: (7R)-4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxoheptyl)oxy]-3,5,9-trioxa-4-phosphahexadecan-1-aminium, inner salt, 4-oxide
Purity: ≥95%
Formula Markup: C22H44NO8P
Formula Weight: 481,6
Shelf life (days): 1460
CAS Number: 39036-04-9
Notes: 1,2-Diheptanoyl-sn-glycero-3-PC (DHPC-C7) is a synthetic phosphatidylcholine containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions. It is commonly used in the formation of lipid bilayers and mixed micelles that has a critical micelle concentration (CMC) of 1.6 mM.{41970,41971} Short-chain phospholipids, such as DHPC-C7 and 1,2-dihexanoyl-sn-glycero-PC (DHPC-C6; Item No. 25585), increase the formation rate of substrate-supported planar phospholipid bilayers on glass and silica.{41971} DHPC-C7 inhibits insulin fibril formation in vitro in a concentration-dependent manner and inhibits cytotoxicity induced by insulin fibril formation in PC12 and SH-SY5Y cells when used at concentrations ranging from 0.5 to 4 mM.{41972}
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