1-A-N

Formulation: A solution in ethanol

Formal Name: 3-(2-((3r,5r,7r)-adamantan-1-yl)acetoxy)-2-((((3-(pyrrolidin-1-yl)propoxy)carbonyl)oxy)methyl)propyl (9Z,12Z,15Z)-octadeca-9,12,15-trienoate

Purity: ≥95%

Formula Markup: C42H67NO7

Formula Weight: 698

Shelf life (days): 730

Notes: 1-A-N is an ionizable cationic lipid (pKa = 6.8) that has been used in the generation of lipid nanoparticles (LNPs) for siRNA delivery in vivo.{51499} LNPs containing 1-A-N and encapsulating siRNA targeting the gene encoding CD45 reduce its gene expression in splenic T cells in mice.

• SKU: CAY40500-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 40500-5
• Package Unit: 5 mg
• Quantity Unit: STK