Formulation: A solution in chloroform
Formal Name: 4,7R-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahentriaconta-13Z,16Z,19Z,22Z,25Z,28Z-hexaen-1-aminium, 4-oxide, inner salt
Purity: ≥90%
Formula Markup: C30H50NO7P
Formula Weight: 567,7
Shelf life (days): 365
CAS Number: 162440-05-3
Notes: 1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-PC is a lysophospholipid containing docosahexaenoic acid (DHA; Item Nos. 90310 / 17950) at the sn-1 position that has been found in shark liver extract.{66132} 1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-PC decreases LPS-induced increases in TNF-α and IL-6 levels in RAW 264.7 cells in a concentration-dependent manner.{66133} It decreases LPS-induced production of nitric oxide (NO) in RAW 264.7 cells when used at concentrations ranging from 12 to 200 µM. 1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-PC (15-500 µg/kg) inhibits plasma leakage into the peritoneum in a mouse model of peritonitis induced by zymosan A (Item No. 21175).
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