Formulation: A crystalline solid
Formal Name: hexadecanoic acid, 2R-hydroxy-3-(phosphonooxy)propyl ester, monosodium salt
Purity: ≥98%
Formula Markup: C19H38O7P • Na
Formula Weight: 432,5
Shelf life (days): 1460
CAS Number: 17618-08-5
Notes: 1-Palmitoyl-2-hydroxy-sn-glycero-3-PA (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of five different G protein-coupled receptors (GPCRs) to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} In addition to playing a role in the aforementioned biological responses, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of Pseudomonas aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.{15000}
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