Formulation: A solution in ethanol
Formal Name: (R)-2-(((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl-16,16,17,17,18,18,19,19,20,20,20-d11)oxy)-3-(stearoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
Purity: ≥99% deuterated forms (d1-d11)
Formula Markup: C46H73D11NO8P
Formula Weight: 821,2
Shelf life (days): 365
Notes: 1-Stearoyl-2-arachidonoyl-d11-sn-glycero-3-PC (SAPC-d11) is intended for use as an internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (Item No. 10009864) by GC- or LC-MS. SAPC is a phospholipid containing stearic acid (Item No. 10011298) and arachidonic acid (Item Nos. 90010 / 90010.1 / 10006607) at the sn-1 and sn-2 positions, respectively. It is a component of LDL and has been found in human stenotic aortic valves and atherosclerotic plaques.{17310,53168} Levels of SAPC are increased in the subepithelial invasive region compared to the superficial region of tumor tissue samples from patients with superficial-type pharyngeal squamous cell carcinoma.{53169} SAPC unilamellar vesicles have been used as substrates to quantify the activity of secretory phospholipase A2 (sPLA2) in the presence or absence of inhibitors.{53170} SAPC has also been used in the formation of lipid bilayers to study the effects of lipid composition on bilayer phase transitions.{53171}
English
Deutsch
