Formulation: A crystalline solid
Formal Name: octadecanoic-2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,17,17,18,18,18-d35 acid, 2,3-dihydroxypropyl-1,1,2,3,3-d5 ester
Purity: ≥99% deuterated forms (d1-d40)
Formula Markup: C21H2D40O4
Formula Weight: 398,8
Shelf life (days): 1460
CAS Number: 2692624-09-0
Notes: 1-Stearoyl-rac-glycerol-d40 is intended for use as an internal standard for the quantification of 1-stearoyl-rac-glycerol (Item No. 26827) by GC- or LC-MS. 1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid (Item No. 10011298) at the sn-1 position. 1-Stearoyl-rac-glycerol levels are decreased in tumor tissue in a mouse model of azoxymethane-induced colorectal carcinogenesis.{48205} Levels of 1-stearoyl-rac-glycerol are decreased in lung tissue from patients with adenocarcinoma, but are increased in the serum of patients with Buruli ulcer and in the cerebrospinal fluid of patients with the inflammatory demyelinating diseases multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and idiopathic transverse myelitis (ITM).{48206,40841,48207} 1-Stearoyl-rac-glycerol has been used in the composition of transfersomes for transdermal delivery of doxorubicin (Item No. 15007) in rats, leading to doxorubicin accumulation in lymph nodes, spleen, and heart.{48208}
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