(±)11-HDHA, CAS 87018-59-5

Formulation: A solution in ethanol

Formal Name: (±)11-hydroxy-4Z,7Z,9E,13Z,16Z,19Z-docosahexaenoic acid

Purity: ≥98%

Formula Markup: C22H32O3

Formula Weight: 344,5

Shelf life (days): 730

CAS Number: 87018-59-5

Notes: (±)11-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.{7479,7491} It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.{7480,7490,7492} DHA is metabolized to 11(S)-HDHA by human platelets and canine retina.{7483,7486,7484,7492} In addition to 11(S)-HDHA, 14(S)-HDHA is also produced by platelets.{7483,7484,7492} 11(S)-HDHA was shown to be an inhibitor of U-46619-induced human platelet aggregation and rabbit and rat aortic smooth muscle contraction with IC50 values of about 50, 4.7, and 7.5 µM, respectively.{7484,7481} (±)11-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.

• SKU: CAY33450-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 33450-100
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK