12(S)-HEPE, CAS 116180-17-7

Formulation: A solution in ethanol

Formal Name: 12S-hydroxy-5Z,8Z,10E,14Z,17Z-eicosapentaenoic acid

Purity: ≥98%

Formula Markup: C20H30O3

Formula Weight: 318,5

Shelf life (days): 365

CAS Number: 116180-17-7

Notes: 12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway.{6402} The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.

• SKU: CAY32550-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 32550-50
• Green Labware: No
• Package Unit: 50 µg
• Quantity Unit: STK