Formulation: A solution in ethanol
Formal Name: (S,5Z,8Z,10E,14Z)-12-hydroxyicosa-5,8,10,14-tetraen-19-ynoic acid
Purity: ≥97%
Formula Markup: C20H28O3
Formula Weight: 316,4
Shelf life (days): 365
Notes: 12(S)-HETE (Item No. 34570) is the predominant lipoxygenase product of mammalian platelets.{498} It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.{591,880} 12(S)-HETE-19,20-alkyne is a form of 12(S)-HETE with an ω-terminal alkyne. The terminal alkyne group can be used in click chemistry linking reactions, to tag 12(S)-HETE with fluorescent or biotinylated labels for analysis of its metabolism and biological activity.{17991,17992}