(±)14-HDHA, CAS 87042-40-8

Formulation: A solution in ethanol

Formal Name: (±)14-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid

Purity: ≥98%

Formula Markup: C22H32O3

Formula Weight: 344,5

Shelf life (days): 730

CAS Number: 87042-40-8

Notes: (±)14-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.{7479,7491} It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.{7480,7490,7492} DHA is metabolized to 14(S)-HDHA by human platelets along with 11(S)-HDHA.{7483,7484,7492} 14(S)-HDoHE is also produced by salmon gills upon stimulation with calcium ionophore.{7514} 14(S)-HDHA was shown to be an inhibitor of U-46619-induced human platelet aggregation and rabbit and rat aortic smooth muscle contraction with IC50 values of about 70, 3.6, and 5.3 µM, respectively.{7484,7481} (±)14-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.

• SKU: CAY33550-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 33550-100
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK