Formulation: A crystalline solid
Formal Name: 9-oxo-11α,15R-dihydroxy-15-methyl-prosta-5Z,13E-dien-1-oic acid
Purity: ≥98%
Formula Markup: C21H34O5
Formula Weight: 366,5
Shelf life (days): 365
CAS Number: 55028-70-1
Notes: 15(R)-15-methyl Prostaglandin E2 (15(R)-15-methyl PGE2) is a prodrug for the potent PGE2 (Item No. 14010) analog 15(S)-15-methyl PGE2 (Item No. 14730).{1994} Acid-catalyzed epimerization in the stomach produces the 15(S)-hydroxy compound which is biologically active.{1150} Oral administration of 15(R)-15-methyl PGE2 to dogs or rats at 10-300 µg/kg results in a dose-dependent inhibition of gastric acid secretion and an increase in the rate of duodenal bicarbonate secretion.{1151,1152}