Formulation: A solution in methyl acetate
Formal Name: 15R-hydroxy-16,16-dimethyl-9-oxo-prosta-10,13E-dien-1-oic acid
Purity: ≥98%
Formula Markup: C22H36O4
Formula Weight: 364,5
Shelf life (days): 365
CAS Number: 41692-24-4
Notes: 16,16-dimethyl Prostaglandin A1 (16,16-dimethyl PGA1) is a metabolism resistant analog of PGA1. In vitro, it inhibits the viral replication in both HSV and HIV-1 infection systems at concentrations that do not adversely alter cellular DNA synthesis. The ID50 for HSV-1 strains in Vero cells and human foreskin fibroblasts are 3.8-5.6 µg/ml and 4.6-7.3 µg/ml, respectively. The ID50 for T cells acutely infected with HIV-1 is 2.5 µg/ml.{811}