Formulation: A solid
Formal Name: 3β,17-dihydroxy-pregn-5-en-20-one
Purity: ≥95%
Formula Markup: C21H32O3
Formula Weight: 332,5
Shelf life (days): 1460
CAS Number: 387-79-1
Notes: 17α-hydroxy Pregnenolone is a metabolite of pregnenolone (Item No. 19864) and a precursor in the biosynthesis of dehydroepiandrosterone (DHEA; Item No. 15728).{53115} It is formed from pregnenolone by cytochrome P450 (CYP) isoform CYP17A1 hydroxylase activity and then converted to dehydroepiandrosterone by CYP17A1-mediated 17,20-lyase activity. Plasma levels of 17α-hydroxy pregnenolone are elevated in patients with type II 3β-hydroxysteroid dehydrogenase deficiency, a form of congenital adrenal hyperplasia.{53116}