Formulation: A solution in methyl acetate
Formal Name: 9Z,12Z-octadecadienoic acid, 2-glyceryl ester
Purity: ≥95% (as a 9:1 mixture of the 2-LG and 1-LG)
Formula Markup: C21H38O4
Formula Weight: 354,5
Shelf life (days): 730
CAS Number: 3443-82-1
Notes: 2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.{4614,5306} The congener of 2-AG in which a linoleoyl group replaces the arachidonoyl group is 2-linoleoyl glycerol (2-LG), and this compound also appears in vivo in conjunction with 2-AG.{9610} Although the intrinsic activity of 2-LG is low, it potentiates the activity of other endocannabinoids, including 2-AG. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.