2-methoxy Estrone, CAS 362-08-3

Formulation: A solid

Formal Name: 3-hydroxy-2-methoxy-estra-1,3,5(10)-trien-17-one

Purity: ≥95%

Formula Markup: C19H24O3

Formula Weight: 300,4

Shelf life (days): 1460

CAS Number: 362-08-3

Notes: 2-methoxy Estrone is an active metabolite of the endogenous estrogen estrone (Item No. 10006485).{54968} It is formed from estrone by catechol-O-methyltransferase (COMT). 2-methoxy Estrone inhibits the proliferation of isolated bovine brain-derived capillary endothelial cells (IC50 = 11.5 µM).{54969} It increases the levels of 6-keto prostaglandin F1α (6-keto PGF1α; Item No. 15210) in human umbilical vein endothelial cells (HUVECs) when used at concentrations of 0.001, 0.01, and 0.1 µM.{54971} 2-methoxy Estrone (0.5 mg/kg) reduces ovariectomy-induced increases in serum cholesterol in rats.{54970}

• SKU: CAY34155-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34155-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK