20-HEPE, CAS 116477-57-7

Formulation: A solution in methyl acetate

Formal Name: 20-hydroxy-5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid

Purity: ≥95%

Formula Markup: C20H30O3

Formula Weight: 318,5

Shelf life (days): 730

CAS Number: 116477-57-7

Notes: 20-HEPE is a metabolite of eicosapentaenoic acid (EPA; Item Nos. 90110 / 21908 / 90110.1) that is formed via ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B.{37628} It activates peroxisome proliferator-activated receptor α (PPARα) in COS-7 cells expressing a luciferase reporter when used at a concentration of 10 μM. 20-HEPE also activates murine transient receptor potential vanilloid receptor 1 (mTRPV1) in vitro but lacks antinociceptive activity in rats.{37629}

• SKU: CAY19322-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19322-25
• Green Labware: No
• Package Unit: 25 µg
• Quantity Unit: STK