20-HETE, CAS 79551-86-3

Formulation: A solution in ethanol

Formal Name: 20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid

Purity: ≥98%

Formula Markup: C20H32O3

Formula Weight: 320,5

Shelf life (days): 365

CAS Number: 79551-86-3

Notes: 20-HETE is a cytochrome P450 (CYP450) metabolite postulated to play an autacoid role in the renal and cerebral vasculature.{7827} In rat cerebral microvessels, 20-HETE is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction.{9023} 20-HETE is excreted mainly as the glucuronide conjugate. The concentration of free 20-HETE (20-40 pg/ml in human urine) is about 10-fold lower than the corresponding concentration of the 20-glucuronide.{1119} 20-HETE can be further metabolized by cyclooxygenase to 20-hydroxy PGG2 and 20-hydroxy PGH2.{380}

• SKU: CAY90030-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 90030-100
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK