20(S)-Protopanaxatriol, CAS 34080-08-5

Formulation: A crystalline solid

Formal Name: (3β,6α,12β)-dammar-24-ene-3,6,12,20-tetrol

Purity: ≥95%

Formula Markup: C30H52O4

Formula Weight: 476,7

Shelf life (days): 1460

CAS Number: 34080-08-5

Notes: 20(S)-Protopanaxatriol is an active aglycone metabolite of various panaxatriol ginsenosides, including ginsenoside Re (Item No. 15330), ginsenoside Rf (Item No. 23667), ginsenoside Rg1 (Item No. 15315), ginsenoside Rg2 (Item No. 15331), and ginsenoside Rh1 (Item No. 27318).{24878} It is cytotoxic to HL-60 cancer cells (IC50 = 16 µM).{53453} 20(S)-Protopanaxatriol inhibits the proliferation of human umbilical vein endothelial cells (HUVECs; EC50 = 6.64 µg/ml).{53454} It inhibits LPS-induced increases in the protein levels of COX-2 and inducible nitric oxide synthase (iNOS) and decreases LPS-induced NF-κB activity in RAW 264.7 cells when used at concentrations ranging from 1 to 20 µM.{53455}

• SKU: CAY29073-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29073-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK