24(R)-hydroxy Cholesterol, CAS 27460-26-0

Formulation: A crystalline solid

Formal Name: cholest-5-ene-3β,24R-diol

Purity: ≥98%

Formula Markup: C27H46O2

Formula Weight: 402,7

Shelf life (days): 730

CAS Number: 27460-26-0

Notes: 24(S)-hydroxy Cholesterol is a side-chain substituted oxysterol that is generated from the action of CYP46 on cholesterol found in the brain and plays an important role in cholesterol homeostasis.{15406} 24(R)-hydroxy Cholesterol is a synthetic enantiomer of 24(S)-hydroxy cholesterol that activates LXRα and LXRβ nuclear receptors with slightly reduced potency (EC50 = 7 and 4 μM, respectively) compared to the natural isomer (EC50 = 4 and 3 μM, respectively).{15406,25539}

• SKU: CAY10217-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10217-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK