24(S),25-epoxy Cholesterol, CAS 77058-74-3

Formulation: A solid

Formal Name: (3β,24S)-24,25-epoxy-cholest-5-en-3-ol

Purity: ≥95%

Formula Markup: C27H44O2

Formula Weight: 400,6

Shelf life (days): 730

CAS Number: 77058-74-3

Notes: 24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs) in the developing ventral midbrain to induce stem cell differentiation into dopaminergic neurons. 24(S),25-epoxy Cholesterol inhibits IL-6 production and degranulation of bone marrow-derived murine mast cells that express LXRβ.{43945} It inhibits the conversion of desmosterol to cholesterol by 3β-hydroxysterol Δ24-reductase (DHCR24/Seladin-1) in CHO-7 and SRD-1 cells when used at a concentration of 2.5 μM.{43944}

• SKU: CAY10131
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10131-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK