25(R)-27-hydroxy Cholesterol, CAS 20380-11-4

Formulation: A crystalline solid

Formal Name: (25R)-cholest-5-ene-3β,26-diol

Purity: ≥95%

Formula Markup: C27H46O2

Formula Weight: 402,7

Shelf life (days): 730

CAS Number: 20380-11-4

Notes: The liver X receptors (LXRα and LXRβ) are nuclear hormone receptors whose native ligands, oxysterols, induce the expression of genes involved in cholesterol and fatty acid metabolism.{12040} 27-hydroxy Cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRα and LXRβ in vitro with EC50 values of 85 and 71 nM, respectively, and is a potent suppressor of cholesterol biosynthesis.{13891,23747} 25(R)-27-hydroxy Cholesterol is the more predominant-occurring (~80%) stereoisomer of the endogenous oxysterol 27-hydroxy cholesterol.{23746,23745}

• SKU: CAY14790-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 14790-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK